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英語論文(2020年以降)
 *2010年代の業績はこちら


 Corresponding authorは名前の後ろに「*」
  1. Ishino T, Watanabe T, Tokita S, Ueda Y, Kawase K, Takano Y, Thu YM, Suzuki Y, Owa C, Inozume T, Zhou W, Nagasaki J, Kochin V, Ueno T, Kojima S, Honobe-Tabuchi A, Kawamura T, Ohnuma T, Matsuzawa T, Kawahara Y, Yamashita K, Lin J, Koseki J, Nishikawa H, Araki M, Kato N, Shimamura T, Morishita S, Suzuki Y, Mano H, Torigoe T, Kanaseki T, Kawazu M, Togashi Y*.
    Immunopeptidomics combined with full-length transcriptomics uncovers diverse neoantigens.
    Cell Rep, 45(1):116781, 2025.
    PMID: 41447530 DOI: 10.1016/j.celrep.2025.116781

  2. Matsuoka A, Shien K, Tomida S, Ohki M, Hisamatsu K, Fujiwara R, Ishimura K, Fujii R, Higashihara T, Hayashi N, Okada K, Yoshichika R, Mukohara F, Yoshikawa M, Fukumoto Y, Suzawa K, Tomioka Y, Tanaka S, Miyoshi K, Okazaki M, Sugimoto S, Otani Y, Tanaka A, Inoue H, Togashi Y, Yamamoto H, Ennishi D, Toyooka S*.
    Single-cell and spatial transcriptomic characterization of pulmonary pleomorphic carcinoma.
    Commun Biol, 8(1):1773, 2025.
    PMID: 41402584 DOI: 10.1038/s42003-025-09162-w

  3. Kanzaki H, Ishino T, Ogasawara S, Tsuchiya T, Fujiya M, Sawada M, Izai R, Akatsuka T, Miwa C, Yonemoto T, Yumita S, Nakagawa M, Kojima R, Koroki K, Inoue M, Kobayashi K, Kanogawa N, Nakamura M, Kondo T, Nakamoto S, Takayashiki T, Takano Y, Takata K, Lin J, Kawazu M, Ikeda JI, Ohtsuka M, Hoshida Y, Komuta M, Togashi Y*.
    The efficacy of atezolizumab plus bevacizumab for advanced hepatocellular carcinoma in relation to tumor-infiltrating lymphocytes.
    JHEP Rep, 7(12):101614, 2025.
    PMID: 41362708 DOI: 10.1016/j.jhepr.2025.101614

  4. Nakao S, Kojima K, Sato K, Kemmotsu N, Ohuchi H, Togashi Y, Sudo Y*.
    Optogenetic Cancer Therapy Using the Light-Driven Outward Proton Pump Rhodopsin Archaerhodopsin-3 (AR3).
    J Am Chem Soc, 147(48):44131-44140, 2025.
    PMID: 41186408 DOI: 10.1021/jacs.5c13053

  5. Kawase K, Kawashima S, Nishi T, Inozume T, Morinaga T, Kawazu M, Hanazawa T, Togashi Y*.
    PI3K/Akt Signaling Pathway Regulates CD155 Expression Involved in Resistance to Cancer Immunotherapy.
    Cancer Immunol Res, 13(10):1640-1654, 2025.
    PMID: 40742385 DOI: 10.1158/2326-6066.CIR-24-0853

  6. Tada R, Yamaguchi T, Kanno T, Endo-Takahashi Y, Hayakawa M, Togashi Y, Yoshizawa S, Adachi Y, Negishi Y*.
    Cavitation bubble-assisted high-intensity focused ultrasound induces abscopal immune responses.
    Int Immunopharmacol, 166:115565, 2025.
    PMID: 40972334 DOI: 10.1016/j.intimp.2025.115565

  7. Nishi T, Morita A, Hara N, Makimoto G, Ninomiya K, Fujii M, Rai K, Ohashi K, Hotta K, Tabata M, Togashi Y, Maeda Y, Ichihara E*.
    Efficacy of amivantamab, a bi-specific antibody targeting EGFR and MET, in ALK-rearranged non-small-cell lung cancer cell lines.
    Lung Cancer, 201:108415, 2025.
    PMID: 39922174, DOI: 10.1016/j.lungcan.2025.108415

  8. Naoi Y, Inukai Y, Izumikawa T, Nagasaki J, Ishino T, Ueda Y, Yin Min Thu, Fujiwara M, Baba T, Makimoto G, Suzawa K, Okada K, Yamamoto K, Sakaguchi M, Tomida S, Maeda Y, Toyooka S, Ando M, Togashi Y*.
    Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity.
    Cancer Immunol Res, In press, 2025
    PMID: 40590673 DOI: 10.1158/2326-6066.CIR-24-1144

  9. Matsuura H, Ishino T, Ninomiya T, Ninomiya K, Tachibana K, Honobe-Tabuchi A, Muto Y, Inozume T, Ueda Y, Ohashi K, Maeda Y, Nagasaki J, Togashi Y*.
    High Antigenicity for Treg Cells Confers Resistance to PD-1 Blockade Therapy via High PD-1 Expression in Treg Cells
    Cancer Sci, 116(5):1214-1226, 2025.
    PMID: 40017103 DOI: 10.1111/cas.70029

  10. Ikeda H, Kawase K, Nishi T, Watanabe T, Takenaga K, Inozume T, Ishino T, Aki S, Lin J, Kawashima S, Nagasaki J, Ueda Y,
    Suzuki S, Makinoshima H, Itami M, Nakamura Y, Tatsumi Y, Suenaga Y, Morinaga T, Honobe-Tabuchi A, Ohnuma T,
    Kawamura T, Umeda Y, Nakamura Y, Kiniwa Y, Ichihara E, Hayashi H, Ikeda J, Hanazawa T, Toyooka S, Mano H, Suzuki T,
    Osawa T, Kawazu M, Togashi Y*.
    Immune evasion through mitochondrial transfer in the tumour microenvironment.
    Nature, 638(8049):225-236, 2025.
    PMID: 39843734, DOI: 10.1038/s41586-024-08439-0

  11. Ninomiya T, Kemmotsu N, Mukohara F, Magari M, Miyamoto A, Ueda Y, Ishino T, Nagasaki J, Fujiwara T, Yamamoto H,
    Hayashi H, Tachibana K, Ishida J, Otani Y, Tanaka S, Toyoda S, Okamoto I, Togashi Y.
    Myeloid Cells Induce Infiltration and Activation of B Cells and CD4+ T Follicular Helper Cells to Sensitize Brain Metastases to Combination Immunotherapy.
    Cancer Res, 85(6):1082-1096, 2025.
    PMID: 39804971, DOI: 10.1158/0008-5472.CAN-24-2274

  12. Nakajima T, Kanno T, Ueda Y, Miyako K, Endo T, Yoshida S, Yokoyama S, Asou HK, Yamada K, Ikeda K, Togashi Y, Endo Y*.
    Fatty acid metabolism constrains Th9 cell differentiation and antitumor immunity via the modulation of retinoic acid receptor signaling.
    Cell Mol Immunol, 21(11):1266-1281, 2024.
    PMID: 39187636 DOI: 10.1038/s41423-024-01209-y

  13. Mukohara F, Iwata K, Ishino T, Inozume T, Nagasaki J, Ueda Y, Suzawa K, Ueno T, Ikeda H, Kawase K, Saeki Y, Kawashima S, Yamashita K, Kawahara Y, Nakamura Y, Honobe-Tabuchi A, Watanabe H, Dansako H, Kawamura T, Suzuki Y, Honda H, Mano H, Toyooka S, Kawazu M, and Togashi Y*.
    Somatic Mutations in Tumor-Infiltrating Lymphocytes Impact on Antitumor Immunity.
    Proc Natl Acad Sci USA, 121(35):e2320189121, 2024.
    PMID: 39167601 DOI: 10.1073/pnas.2320189121

  14. Fujimoto T, Yamasaki O, Kanehira N, Matsushita H, Sakurai Y, Kenmotsu N, Mizuta R, Kondo N, Takata T, Kitamatsu M, Igawa K, Fujimura A, Otani Y, Shirakawa M, Shigeyasu K, Teraishi F, Togashi Y, Suzuki M, Fujiwara T, Michiue H*.
    Overcoming immunotherapy resistance and inducing abscopal effects with boron neutron immunotherapy (B-NIT)
    Cancer Sci, 115(10):3231-3247, 2024.
    PMID: 39119813 DOI: 10.1111/cas.16298

  15. Okumura K, Morinaga T, Saito M, Tokunaga Y, Otoyama K, Tanaka S, Isogai E, Kawazu M, Togashi Y, Hasegawa Y, Wakabayashi Y*.
    Targeting PAK1 is effective against cutaneous squamous cell carcinoma in a syngenic mouse model.
    Cancer Sci, 115(8):2839-2845, 2024.
    PMID: 38898727 DOI: 10.1111/cas.16246

  16. Tsukada Y*, Bando H, Inamori K, Wakabayashi M, Togashi Y, Koyama S, Kotani D, Yuki S, Komatsu Y, Homma S, Taketomi A, Uemura M, Kato T, Fukui M, Nakamura N, Kojima M, Kawachi H, Kirsch R, Yoshida T, Sato A, Nishikawa H, Ito M, Yoshino T.
    Three-year outcomes of preoperative chemoradiotherapy plus nivolumab in microsatellite stable and microsatellite instability-high locally advanced rectal cancer.
    Br J Cancer, 131(2):283-289, 2024.
    PMID: 38834744 DOI: 10.1038/s41416-024-02730-7

  17. Naoi Y, Morinaga T, Nagasaki J, Ariyasu R, Ueda Y, Yamashita K, Zhou W, Kawashima S, Kawase K, Honobe-Tabuchi A, Ohnuma T, Kawamura T, Umeda Y, Kawahara Y, Nakamura Y, Kiniwa Y, Yamasaki O, Fukushima S, Kawazu M, Suzuki Y, Nishikawa H, Hanazawa T, Ando M, Inozume T, Togashi Y*.
    CD106 in tumor-specific exhausted CD8+ T cells mediates immunosuppression by inhibiting TCR signaling.
    Cancer Res, 84(13):2109-2122, 2024.
    DOI: 10.1158/0008-5472.CAN-23-0453 PMID: 38635899

  18. Hayashi H, Chamoto K, Hatae R, Kurosaki T, Togashi Y, Fukuoka K, Goto M, Chiba Y, Tomida S, Ota T, Haratani K, Takahama T, Tanizaki J, Yoshida T, Iwasa T, Tanaka K, Takeda M, Hirano T, Yoshida H, Ozasa H, Sakamori Y, Sakai K, Higuchi K, Uga H, Suminaka C, Hirai T, Nishio K, Nakagawa K, Honjo T*.
    Soluble immune checkpoint factors reflect exhaustion of antitumor immunity and response to PD-1 blockade.
    J Clin Invest, 134(7):e168318, 2024.
    PMID: 38557498 DOI: 10.1172/JCI168318

  19. Zhou W, Kawashima S, Ishino T, Kawase K, Ueda Y, Yamashita K, Watanabe T, Kawazu M, Dansako H, Suzuki Y, Nishikawa H, Inozume T, Nagasaki J*, Togashi Y*.
    Stem-like Progenitor and Terminally Differentiated TFH-like CD4+ T cell Exhaustion in the Tumor Microenvironment
    Cell Rep, 43(2):113797, 2024.
    DOI: 10.1016/j.celrep.2024.113797 PMID: 38363680

  20. Okumura K, Morinaga T, Saito M, Tokunaga Y, Otoyama K, Tanaka S, Isogai E, Kawazu M, Togashi Y, Araki K, Wakabayashi Y*.
    Deletion of Pak1 in CD11c positive cells confers resistance to mouse skin carcinogenesis.
    J Invest Dermatol, 144(8):1890-1893.e5, 2024.
    DOI: 10.1016/j.jid.2024.01.021 PMID: 38325578

  21. Dansako H*, Ikeda M, Ariumi Y, Togashi Y, Kato N.
    Hepatitis C virus NS5B triggers an MDA5-mediated innate immune response by producing dsRNA without the replication of viral genomes.
    FEBS J, 291(6):1119-1130, 2024
    DOI: 10.1111/febs.16980 PMID: 37863517

  22. Kemmotsu N, Ninomiya K, Kunimasa K, Ishino T, Nagasaki J, Otani Y, Michiue H, Ichihara E, Ohashi K, Inoue T, Tamiya M, Sakai K, Ueda Y, Dansako H, Nishio K, Kiura K, Date I, Togashi Y*.
    Low frequency of intracranial progression in advanced NSCLC patients treated with cancer immunotherapies.
    Int J Cancer, 154(1):169-179, 2024.
    DOI:10.1002/ijc.34700 PMID:37611176

  23. Immunological Significance of CD80/CD86 or Major Histocompatibility Complex-II Expression in Thymic Epithelial Tumors.
    Ikeda H, Nagasaki J, Shimizu D, Katsuya Y, Horinouchi H, Hosomi Y, Tanji E, Iwata T, Itami M, Kawazu M, Ohe Y, Suzuki T, Togashi Y*.
    JTO Clin Res Rep, 4(10):100573, 2023.
    DOI: 10.1016/j.jtocrr.2023.100573 PMID: 37799325

  24. Kemmotsu N, Zhu L, Nagasaki J, Otani Y, Ueda Y, Dansako H, Fang Y, Date I, Togashi Y*.
    Combination therapy with hydrogen peroxide and irradiation promotes an abscopal effect in mouse models.
    Cancer Sci, 114(10):3848-3856, 2023.
    DOI:10.1111/cas.15911 PMID:37485636

  25. Watanabe T, Ishino T, Ueda Y, Nagasaki J, Sadahira T, Dansako H, Araki Motoo, Togashi Y*.
    Activated CTLA-4-independent immunosuppression of Treg cells disturbs CTLA-4 blockade-mediated antitumor immunity.
    Cancer Sci, 114(5):1859-1870, 2023.
    DOI:10.1111/cas.15756 PMID:36762794

  26. Kawase K, Kawashima S, Nagasaki J, Inozume T, Tanji E, Kawazu M, Hanazawa T, Togashi Y*.
    High Expression of MHC Class I Overcomes Cancer Immunotherapy Resistance Due to IFNγ Signaling Pathway Defects.
    Cancer Immunol Res, 11(7):895-908, 2023
    DOI:10.1158/2326-6066.CIR-22-0815 PMID:37062030

  27. Ishino T, Kawashima S, Tanji E, Ueno T, Ueda Y, Ogasawara S, Sato K, Mano H, Ishihara S, Kato N, Kawazu M*, Togashi Y*.
    Somatic mutations can induce a noninflamed tumour microenvironment via their original gene functions, despite deriving neoantigens
    Br J Cancer ,128(6):1166-1175, 2023.
    DOI:10.1038/s41416-023-02165-6 PMID:36732592

  28. Shingaki S, Koya J, Yuasa M, Saito Y, Tabata M, McClure MB, Ogawa S, Katayama K, Togashi Y, Imoto S, Kogure Y, Kataoka K*.
    Tumor-promoting function and regulatory landscape of PD-L2 in B-cell lymphoma.
    Leukemia, 37(2):492-496, 2023.
    DOI:10.1038/s41375-022-01772-1 PMID:36522456

  29. Kawashima S, Togashi Y*.
    Resistance to immune checkpoint inhibitors and the tumor microenvironment.
    Exp Dermatol. 32(3):240-249, 2023.
    DOI:10.1111/exd.14716 PMID:36437644

  30. Nagasaki J, Ishino T, Togashi Y*.
    Mechanisms of resistance to immune checkpoint inhibitors.
    Cancer Sci, 113:3303-3312, 2022.
    DOI:10.1111/cas.15497 PMID:35848888

  31. Nagasaki J, Togashi Y*.
    A variety of 'exhausted' T cells in the tumor microenvironment.
    Int Immunol, 34:563-570, 2022.
    DOI:10.1093/intimm/dxac013 PMID:35460561

  32. Ymamoto H, Togashi Y*.
    Programmed Death-Ligand 1 Rich Premetastatic Niche in Adjuvant Chemotherapy.
    J Thorac Oncol, 17(1):10-12, 2022.
    DOI 10.1016/j.jtho.2021.10.019 : PMID:34930604

  33. Ikeda H, Togashi Y*.
    Aging, cancer, and antitumor immunity.
    Int J Clin Oncol, 27:316-322, 2022.
    DOI:10.1007/s10147-021-01913-z PMID:33783658

  34. Bando H, Tsukada Y, Inamori K, Togashi Y, Koyama S, Kotani D, Fukuoka S, Yuki S, Komatsu Y, Homma S, Taketomi A, Uemura M, Kato T, Fukui M, Wakabayashi M, Nakamura N, Kojima M, Kawachi H, Kirsch R, Yoshida T, Suzuki Y, Sato A, Nishikawa H, Ito M, Yoshino T*.
    Preoperative Chemoradiotherapy plus Nivolumab before Surgery in Patients with Microsatellite Stable and Microsatellite Instability-High Locally Advanced Rectal Cancer.
    Clin Cancer Res, 28(6):1136-1146, 2022.
    DOI:10.1158/1078-0432.CCR-21-3213 PMID: 35063964

  35. Kumagai S, Koyama S*, Itahashi K, Tanegashima T, Lin YT, Togashi Y, Kamada T, Irie T, Okumura G, Kono H, Ito D, Fujii R, Watanabe S, Sai A, Fukuoka S, Sugiyama E, Watanabe G, Owari T, Nishinakamura H, Sugiyama D, Maeda Y, Kawazoe A, Yukami H, Chida K, Ohara Y, Yoshida T, Shinno Y, Takeyasu Y, Shirasawa M, Nakama K, Aokage K, Suzuki J, Ishii G, Kuwata T, Sakamoto N, Kawazu M, Ueno T, Mori T, Yamazaki N, Tsuboi M, Yatabe Y, Kinoshita T, Doi T, Shitara K, Mano H, Nishikawa H*.
    Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments.
    Cancer Cell, 40(2):201-218, 2022.
    DOI: 10.1016/j.ccell.2022.01.001 PMID:35090594

  36. Nagasaki J, Inozume T, Sax N, Ariyasu R, Ishikawa M, Yamashita K, Kawazu M, Ueno T, Irie T, Tanji E, Morinaga T, Honobe A, Ohkura T, Yoshino M, Iwata T, Kawase K, Sasaki K, Hanazawa t, Kochin V, Kawamura T, Matsue H, Hino M, Mano, H, Suzuki Y, Nishikawa H, Togashi Y*.
    PD-1 blockade therapy promotes infiltration of tumor-attacking exhausted T cell clonotypes.
    Cell Rep, 38(5):110331, 2022.
    DOI:10.1016/j.celrep.2022.110331 PMID:35108529

  37. Kawazu M*, Ueno T, Saeki K, Sax N, Togashi Y, Kaneseki T, Chida K, Kishigami F, Sato K, Kojima S, Otsuka M, Kawazoe A, Nishinakamura H, Maeda Y, Yamamoto Y, Yamashita K, Inoue S, Tanegashima T, Matsubara D, Tane K, Tanaka Y, Iinuma H, Hashiguchi Y, Hazama S, Khor SS, Tokunaga K, Tsuboi M, Niki T, Eto M, Shitara K, Torigoe T, Ishihara S, Aburatani H, Haeno H, Nishikawa H, Mano H.
    HLA Class I analysis provides insight into the genetic and epigenetic background of immune evasion in colorectal cancer with high microsatellite instability.
    Gastroenteology, 162(3):799-812, 2022.
    DOI:10.1053/j.gastro.2021.10.010 PMID:34687740

  38. Morinaga T, Inozume T, Kawazu M, Ueda Y, Sax N, Yamashita K, Kawashima S, Nagasaki J, Ueno T, Lin J, Ohara Y, Kuwata T, Yukami H, Kawazoe A, Shitara K, Honobe-Tabuchi A, Ohnuma T, Kawamura T, Umeda Y, Kawahara Y, Nakamura Y, Kiniwa Y, Morita A, Ichihara E, Kiura K, Enokida T, Tahara M, Hasegawa Y, Mano H, Suzuki Y, Nishikawa H, Togashi Y*.
    Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration.
    Cancer Res Commun, 2(7):739-753, 2022.
    DOI: 10.1158/2767-9764.CRC-22-0050 PMID: 36923281

  39. Namba S, Ueno T, Kojima S, Kobayashi K, Kawase K, Tanaka Y, Inoue S, Kishigami F, Kawashima S, Maeda N, Ogawa T, Hazama S, Togashi Y, Ando M, Shiraishi Y, Mano H, Kawazu M*.
    Transcript-targeted analysis reveals isoform alterations and double-hop fusions in breast cancer.
    Commun Biol, 4(1):1320, 2021.
    DOI:10.1038/s42003-021-02833-4 PMID:34811492

  40. Kawashima S, Inozume T, Kawazu M, Ueno T, Nagasaki J, Tanji E, Honobe A, Ohnuma T, Kawamura T, Umeda Y, Nakamura Y, Kawasaki T, Kiniwa Y, Yamasaki O, Fukushima S, Ikehara Y, Mano H, Suzuki Y, Nishikawa H, Matsue H, Togashi Y*.
    TIGIT/CD155 axis mediates resistance to immunotherapy in melanoma patients with the inflamed tumor microenvironment.
    J Immunother Cancer, 9(11):e003134, 2021.
    DOI: 10.1136/jitc-2021-003134 PMID:34795004

  41. Takeuchi Y, Tanegashima T, Sato E, Irie T, Sai A, Itahashi K, Kumagai S, Tada Y, Togashi Y, Koyama S, Akbay EA, Karasaki T, Kataoka K, Funaki S, Shintani Y, Nagatomo I, Kida H, Ishii G, Miyoshi T, Aokage K, Kakimi K, Ogawa S, Okumura M, Eto M, Kumanogoh A, Tsuboi M, Nishikawa H.
    Highly immunogenic cancer cells require activation of the WNT pathway for immunological escape.
    Sci Immunol, 6(65):eabc6424, 2021.
    DOI10.1126/sciimmunol.abc6424 : PMID:34767457

  42. Koya J, Saito Y, Kameda T, Kogure Y, Yuasa M, Nagasaki J, McClure MB, Shingaki S, Tabata M, Tahira Y, Akizuki K, Kamiunten A, Sekine M, Shide K, Kubuki Y, Hidaka T, Kitanaka A, Nakano N, Utsunomiya A, Togashi Y, Ogawa S, Shimoda K, Kataoka K.
    Single-Cell Analysis of the Multicellular Ecosystem in Viral Carcinogenesis by HTLV-1.
    Blood Cancer Discov, 2(5):450-467, 2021.
    DOI:10.1158/2643-3230.BCD-21-0044 PMID:34661162

  43. Dansako H*, Ueda Y, Satoh S, Kato N.
    Extracellular vesicles activate ATM-Chk2 signaling pathway through the intercellular transfer of mitochondrial DNA in HBV-infected human hepatocytes.
    FASEB J, 35(6):e21680, 2021.
    DOI:10.1096/fj.202002678R PMID:34042225

  44. Inamori K, Togashi Y*, Fukuoka S, Akagi K, Ogasawara K, irie T, Motooka D, Kobayashi Y, Sugiyama D, Kojima M, Shiiya N, Nakamura S, Murayama S, Suzuki Y, Ito M, Nishikawa H.
    Importance of lymph node immune responses in MSI-H/dMMR colorectal cancer.
    JCI Insight, 6:137365, 2021.
    DOI:10.1172/jci.insight.137365 PMID:33755600

  45. Watanabe S, Goto Y, Yasuda H, Kohno T, Motoi N, Ohe Y, Nishikawa H, Kobayashi SS, Kuwano K, Togashi Y.
    HSP90 inhibition overcomes EGFR amplification-induced resistance to third-generation EGFR-TKIs.
    Thorac Cancer, 12:631-642, 2021.

  46. Arakawa A, Ichikawa H, Kubo T, Motoi N, Kumamoto T, Nakajima M, Yonemori K, Noguchi E, Sunami K, Shiraishi K, Kakishima H, Yoshida H, Hishiki T, Kawakubo N, Kuroda T, Kiyokawa T, Yamada K, Yanaihara N, Takahashi K, Okamoto A, Hirabayashi S, Hasegawa D, Manabe A, Ono K, Matsuoka M, Arai Y, Togashi Y, Shibata T, Nishikawa H, Aoki K, Yamamoto N, Kohno T, Ogawa C.
    Vaginal Transmission of Cancer from Mothers with Cervical Cancer to Infants.
    N Engl J Med, 384:42-50, 2021.

  47. Kashima Y, Togashi Y (equally contribution), Fukuoka S, Kamada T, Irie T, Suzuki A, Nakamura Y, Shitara K, Minamide T, Yoshida T, Taoka N, Kawase T, Wada T, Inaki K, Chihara M, Ebisuno Y, Tsukamoto S, Fujii R, Ohashi A, Suzuki Y, Tsuchihara K, Nishikawa H, Doi T.
    Potentiality of multiple modalities for single-cell analyses to evaluate the tumor microenvironment in clinical specimens.
    Sci Rep, 11:341, 2021.

  48. Gu W, Ueda Y, Dansako H, Satoh S, Kato N.
    Antiviral mechanism of preclinical antimalarial compounds possessing multiple antiviral activities.
    FASEB BioAdv, 3(5):356-373, 2021.
    DOI:10.1096/fba.2020-00107 PMID:33977235

  49. Honobe A, Sakai K, Togashi Y, Ohnura T, Kawamura T, Nishio K, Inozume T.
    Heterogeneity in congenital melanocytic nevi contributes muliticentric melanomagenesis.
    J Dermatol Sci, 100:217-219, 2020.

  50. Hayashi H, Takiguchi Y, Minami H, Akiyoshi K, Segawa Y, Ueda H, Iwamoto Y, Kondoh C, Matsumoto K, Takahashi S, Yasui H, Sawa T, Onozawa Y, Chiba Y, Togashi Y, Fujita Y, Sakai K, Tomida S, Nishio K, Nakagawa K.
    Site-Specific and Targeted Therapy Based on Molecular Profiling by Next-Generation Sequencing for Cancer of Unknown Primary Site: A Nonrandomized Phase 2 Clinical Trial.
    JAMA Oncol, 15:1-9, 2020.

  51. Nagasaki J, Togashi Y*, Sugawara T, Itami M, Yamauchi N, Yuda J, Sugano M, Ohara Y, Minami Y, Nakamae H, Hino M, Takeuchi M, Nishikawa H.
    The critical role of CD4+ T cells in PD-1 blockade against MHC-II-expressing tumors such as classical Hodgkin lymphoma.
    Blood Adv, 4:4069-4082, 2020.

  52. Kawazoe A, Kuboki Y, Shinozaki E, Hara H, Nishina T, Komatsu Y, Yuki S, Wakabayashi M, Nomura S, Sato A, Kuwata T, Kawazu M, Mano H, Togashi Y, Nishikawa H, Yoshino T.
    Multicenter phase 1/2 trial of napabucasin and pembrolizumab in patients with metastatic colorectal cancer (EPOC1503).
    Clin Cancer Res, 26:5887-5894, 2020.

  53. Sato K, Mimaki S, Yamashita R, Togashi Y, Naito T, Udagawa H, Nakamura H, Katsumata S, Nakasone S, Tane K, Miyoshi T, Aokage K, Sugano M, Kojima M, Fujii S, Kuwata T, Ochiai A, Goto K, Tsuboi M, Tssuchihara K, Ishii G.
    Association between the mutational smoking signature and the immune microenvironment in lung adenocarcinoma.
    Lung Cancer, 147:12-20, 2020.

  54. Kumagai S, Togashi Y (equally contribution), Kamada T, Sugiyama E, Nishinakamura H, Takeuchi Y, Kochin V, Itahashi K, Maeda Y, Matsui S, Shibahara T, Yamashita Y, Irie T, Tsuge A, Fukuoka S, Kawazoe A, Udagawa H, Kirita K, Aokage K, Ishii G, Kuwata T, Nakama K, Kawazu M, Ueno T, Yamazaki N, Goto K, Tsuboi M, Mano H, Doi T, Shitara K and Nishikawa H.
    The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies.
    Nat Immunol, 21:1346-1358, 2020.

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